Mezcal Production. There are dedicated denominations of origin for mezcal, covering nine Mexican states: Durango, Guerrero, Guanajuato, Michoacán, Oaxaca Puebla, San Luis Potosí, Tamaulipas, and Zacatecas. ... ground down by a stone mill known as a tahona (with the wheel pulled by donkey or horse), fermented, distilled twice, ...